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Outline
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THE MOLECULES OF CELLS
  • INTRODUCTION TO ORGANIC AND BIOCHEMISTRY
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CARBON
  • Carbon is the basis for the natural world (biological) because of its ability to bond to itself in long chains or rings.
  • Carbon will also covalently bond to H2,N2,O2, S and the halogens.
  • All bio-molecules are the result of these bondings, such as skin, cells, fur, feathers, hides, carbohydrates, fats, proteins, dyes, insecticides, perfumes, flavorings and foods.


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CARBON
  • Fossil fuels, plastics, rubber, synthetic and natural fibers, artificial sweeteners, drugs are the result of research into organic chemistry.
  • There are more than 6 million organic compounds known; only 60,000 inorganic compounds are known.



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PROPERTIES OF ORGANIC COMPOUNDS
  • Most properties are determined by the bonding between the C-C and the C-other elements.
  • Carbon has 4 electrons in its valence level and each electron forms a covalent sp3 hybrid bond with another carbon or other element.


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HYDROCARBONS
  • Hydrocarbons are the compounds composed only of carbon and hydrogen.
  • These compounds can be saturated or unsaturated.
  • Saturated hydrocarbons have single bonds between the carbons and are saturated with the most hydrogens it can hold.
  • Unsaturated have double or triple bonds between the carbons.


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NAMING HYDROCARBONS
  • The hydrocarbons are divided into classes based on the single, double or triple bonds:
  • Alkanes are single bonded
  •    Alkenes are double bonded
  • Alkynes are triple bonded
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HYDROCARBON DERIVATIVES
  • Hydrocarbon derivatives are organic molecules that contain more elements than just carbon and hydrogen.
  • The portion of the chain that contains other elements is called the functional group.
  • Each functional group causes the molecule to exhibit characteristics that are special to that group.
  • The remainder of the chain is designated as the R- group.


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POLARITY
  • The functional group can be hydrophilic (water-loving) which creates a polar end to the molecule and therefore it will dissolve in water.
  •                       OR
  • Hydrophobic (water-fearing) which means it has no polar end so will not dissolve in water.
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FUNCTIONAL GROUPS
  • There are four functional groups that are commonly found in molecules made by or used by organisms:
  • 1.    Hydroxyl (-OH) is bonded to the carbon chain either at the end of the chain or in the middle.  This group is called the alcohols and includes methanol, ethanol and propanol.
  •  They are named by dropping the –e of the root name and adding –ol.
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FUNCTIONAL GROUPS
  • 2.  A Carbonyl group has a double bonded oxygen atom attached to a carbon.
  •                -C=O
  • If the carbonyl is on the end of the chain, it is an aldehyde.  These are named by dropping the -e of the root name and adding –al. ex. Methanal, ethanal.
  • If the carbonyl is in the middle of a chain, it is a ketone.  These are named by dropping the –e of the root name and adding –one. Ex. Propanone (acetone), butanone.
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FUNCTIONAL GROUPS
  • 3. The carboxyl group combines the hydroxyl and carbonyl to make a carbon on the end of a chain have a double-bonded oxygen atom and a hydroxyl group.  These compounds will lose a H+ making them act like acids.
  • They are named by dropping the –e of the root name and adding -oic with acid.
  • Ex. Methanoic acid (formic acid), ethanoic acid (acetic acid-vinegar)
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FUNCTIONAL GROUPS
  • 4. The amine group adds a nitrogen atom to the carbon chain, either at the end or in the middle of the chain. They are named by dropping the -e of the root named and adding -amine.  Ex. Methanamine, ethanamine.
  • If the amine replaces the hydroxyl on an acid, it is called an amino acid group.
  • These have there own names such as glycine, alanine.
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FUNCTIONAL GROUPS
  • Many compounds have more than one functional group.
  • Most sugars have hydroxyl and carbonyl groups in the carbon chain.
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MACROMOLECULES
  • Macromolecules consist of thousands of atoms that are bonded together in a certain way.
  • They are put together from smaller molecules called monomers to form one long polymer.
  • The 4 classes of macromolecules are carbohydrates, proteins, lipids, and nucleic acids
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MACROMOLECULES
  • To form these macromolecules, the cell will combine the monomers by removing a hydroxyl group from one monomer and a hydrogen from another to make a water molecule.  This is called dehydration synthesis or condensation reaction.
  • When the cell needs to use the macromolecule, it can perform hydrolysis, which breaks the covalent bond that joins the monomers and breaks the polymer apart.