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- INTRODUCTION TO ORGANIC AND BIOCHEMISTRY
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- Carbon is the basis for the natural world (biological) because of its
ability to bond to itself in long chains or rings.
- Carbon will also covalently bond to H2,N2,O2,
S and the halogens.
- All bio-molecules are the result of these bondings, such as skin, cells,
fur, feathers, hides, carbohydrates, fats, proteins, dyes, insecticides,
perfumes, flavorings and foods.
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- Fossil fuels, plastics, rubber, synthetic and natural fibers, artificial
sweeteners, drugs are the result of research into organic chemistry.
- There are more than 6 million organic compounds known; only 60,000
inorganic compounds are known.
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- Most properties are determined by the bonding between the C-C and the
C-other elements.
- Carbon has 4 electrons in its valence level and each electron forms a
covalent sp3 hybrid bond with another carbon or other
element.
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- Hydrocarbons are the compounds composed only of carbon and hydrogen.
- These compounds can be saturated or unsaturated.
- Saturated hydrocarbons have single bonds between the carbons and are
saturated with the most hydrogens it can hold.
- Unsaturated have double or triple bonds between the carbons.
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- The hydrocarbons are divided into classes based on the single, double or
triple bonds:
- Alkanes are single bonded
- Alkenes are double bonded
- Alkynes are triple bonded
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- Hydrocarbon derivatives are organic molecules that contain more elements
than just carbon and hydrogen.
- The portion of the chain that contains other elements is called the functional
group.
- Each functional group causes the molecule to exhibit characteristics
that are special to that group.
- The remainder of the chain is designated as the R- group.
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- The functional group can be hydrophilic (water-loving) which creates a
polar end to the molecule and therefore it will dissolve in water.
- OR
- Hydrophobic (water-fearing) which means it has no polar end so will not
dissolve in water.
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- There are four functional groups that are commonly found in molecules
made by or used by organisms:
- 1. Hydroxyl (-OH) is bonded to
the carbon chain either at the end of the chain or in the middle. This group is called the alcohols and
includes methanol, ethanol and propanol.
- They are named by dropping the –e
of the root name and adding –ol.
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- 2. A Carbonyl group has a double
bonded oxygen atom attached to a carbon.
- -C=O
- If the carbonyl is on the end of the chain, it is an aldehyde. These are named by dropping the -e of
the root name and adding –al. ex. Methanal, ethanal.
- If the carbonyl is in the middle of a chain, it is a ketone. These are named by dropping the –e of
the root name and adding –one. Ex. Propanone (acetone), butanone.
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- 3. The carboxyl group combines the hydroxyl and carbonyl to make a
carbon on the end of a chain have a double-bonded oxygen atom and a
hydroxyl group. These compounds
will lose a H+ making them act like acids.
- They are named by dropping the –e of the root name and adding -oic with
acid.
- Ex. Methanoic acid (formic acid), ethanoic acid (acetic acid-vinegar)
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- 4. The amine group adds a nitrogen atom to the carbon chain, either at
the end or in the middle of the chain. They are named by dropping the -e
of the root named and adding -amine.
Ex. Methanamine, ethanamine.
- If the amine replaces the hydroxyl on an acid, it is called an amino
acid group.
- These have there own names such as glycine, alanine.
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- Many compounds have more than one functional group.
- Most sugars have hydroxyl and carbonyl groups in the carbon chain.
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- Macromolecules consist of thousands of atoms that are bonded together in
a certain way.
- They are put together from smaller molecules called monomers to form one
long polymer.
- The 4 classes of macromolecules are carbohydrates, proteins, lipids, and
nucleic acids
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- To form these macromolecules, the cell will combine the monomers by
removing a hydroxyl group from one monomer and a hydrogen from another
to make a water molecule. This is
called dehydration synthesis or condensation reaction.
- When the cell needs to use the macromolecule, it can perform hydrolysis,
which breaks the covalent bond that joins the monomers and breaks the
polymer apart.
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